First open source all-atom models of Covid-19 ‘spike’ protein produced

Must read

How to disable and delete Samsung Pay from your Galaxy phone

When it comes to paying conveniently, Samsung Pay makes using your phone as a bank card an easy process; however, there may come...

Should I buy an SSD for my PS4 or PS4 Pro?

Wondering whether you should buy an SSD for your PS4 or PS4 Pro? Then you've landed on the right page. Solid-state storage is...

You Really Are Better Off Spending Your Money On An HP Omen 15 Gaming Laptop

As we resume the Intel vs AMD battles in earnest again, after many years, the Dell G5 15 SE gaming laptop sits very...

Games of the Generation: Stardew Valley is a welcome break from the chaos of the world

Games of the GenerationAs we approach the launch of the PS5 and Xbox Series X, TechRadar is looking back at the games that...
Bhawani Singhhttps://techmepro.com
I am a blogger who believes in delivering latest tech news from around the world to my viewers.

lONDON: Scientists have produced the first open source all-atom models of full-length spike protein of the novel coronavirus that facilitates its entry into the host cells, an advance that may aid faster Covid-19 vaccine and antiviral drug development. The “spike” or S protein of SARS-CoV-2 virus that causes Covid-19 facilitates viral entry into host cells, according to the researchers, including those from the University of Cambridge in the UK.
This makes S protein the main target for vaccine and antiviral drug development, they said.
Described in The Journal of Physical Chemistry B, CHARMM-GUI is a programme that simulates complex biomolecular systems simply, precisely and quickly.
Wonpil Im, a professor at Lehigh University in the US, describes it as a “computational microscope” that enables scientists to understand molecular-level interactions that cannot be observed any other way.
“Our models are the first fully-glycosylated full-length SARS-CoV-2 spike (S) protein models that are available to other scientists,” said Im, who developed the programme.
Scientists can use the models to conduct innovative and novel simulation research for the prevention and treatment of Covid-19, according to Im.
The researchers first modelled the missing amino acid residues, and then other missing domains.
They also modelled all potential glycans (or carbohydrates) attached to the S protein.
These glycans prevent antibody recognition, which makes it difficult to develop a vaccine.
The researchers also built a viral membrane system of an S protein for molecular dynamics simulation.

Source link


More articles

Leave a Reply

Subscribe to our newsletter

To be updated with all the latest news, offers and special announcements.

- Advertisement -

Latest article

Google Pixel 5 Users Report Issues With Pixel Stand, No Fix in Sight

Google Pixel 5 users have been experiencing issues when placing their phones on the Pixel Stand, as per the Pixel support page and...

OnePlus launches IDEAS 2.0 to help improve OxygenOS

Having one of the most active online communities has seen OnePlus become a major player in the Android space over the past few...

India’s most beautiful, most respected, most versatile celebrities in pics

Deepika Padukone is also India’s Most Glamorous with a top score 60.3. In Bollywood, Priyanka Chopra and Ranbir Kapoor are seen to have...

Fears over 'weakening' of UK green watchdog

Campaigners fear that a body designed to protect the environment is being undermined. Source link

TikTok shrugs off Trump attack with expansion plans

Anti-Trump TikTokkers not declaring paid content Source link
- Advertisement -